ROKIT BIO PRINT

Essential Explanations of 3D Printing

Kerry Stevenson (General Fabb)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Rokit’s Sophisticated BioPrinter

ROKIT's new Invivo 3D bioprinter

There are not very many bioprinters on the market, but one of the more sophisticated options is the Invivo from ROKIT. 

Korea-based ROKIT is perhaps best known for their broad line of 3Dison 3D printers, which cover almost the entire range of needs for plastic 3D printing, from hobbyist to professional usage. But evidently their plans involve going well beyond plastic 3D printing and now enter the biological world with the introduction of the Invivo Bioprinter. 

This device is similar to plastic 3D printers, but used in an utterly different manner. Instead of heating plastic to a flowing state and extruding, the bioprinter merely deposits biomaterial. In fact, heating the material would destroy it! 

Bioprinters operate with an approach similar to a support-structure as used with plastic prints. However, the support structure, called a “scaffold”, is made from biodegradable material. Upon this structure is also deposited the “active” material, which is typically live cells. 

The resulting print is placed in a culture medium, where the living cells multiply and the scaffold eventually dissolves. This leaves a biostructure of only the desired living cells. 

This technique is used to create, for example, a replacement human ear: an ear-shaped scaffold is filled with live cells that “become” the ear. Presumably the ear is custom designed to fit the specific individual. 

 

 

The dual extruders on the ROKIT Invivo 3D bioprinter

But back to the new Invivo machine. The most prominent feature of the device is that it includes dual extruders, permitting the printing of both scaffold and biological material at the same time. This should simplify and speed up bioprinting when the Invivo is used. 

Aside from the dual extruders, the device itself has a sophisticated design that would definitely fit within any proper lab environment. I mention this because many of the bioprinters I’ve previously seen have been quite rudimentary in their design. Here, for example, you can see the Invivo’s detailed - and large - touch control panel. 

 

 

 

 

 

 

 

 

 

 

 

 

 

The touch control panel on the ROKIT Invivo 3D bioprinter

The exterior case is notable not only for it’s professional appearance, but that there IS an exterior case! Many other primitive bioprinters are simply a basic armature holding up the mechanical axes. This device is for real, and intended for professional use. 

What’s also interesting is the materials specification for the Invivo. The scaffold extruder is capable of extruding several different materials: 

  • PLGA (poly lactic-co-gylcolic acid)

  • PLLA (poly L Lactic acid)

  • PCL (polycaprolactone)

  • PLA (polylactic acid)

Whereas the bio-extruder can print these materials:

  • Collagen

  • Alginates

  • Silk Fibroin

  • Hyaluronic Acid

The nozzle size can also be changed to several different diameters, depending on the application. 

The Invivo also includes the ability to pre-heat materials to precise temperatures before extruding, and can be upgraded to include a heated - and cooling (!) bed. This permits precise treatment of fragile print materials during operation. 

Needless to say, the Invivo uses bio-safe components and has been medically certified for such uses as printing small and simple replacement parts for humans. 

General Fabb

Kerry Stevenson, aka "General Fabb" has been writing Fabbaloo posts since he launched the venture in 2007, with an intention to promote and grow the incredible technology of 3D printing across the world. So far, it seems to be working!

© Copyright Terran Data Corporation, 2018

What's New at ROKIT

FRAUNHOFER IBMT, GERMANY VISITED ROKIT FOR RESEARCH COOPERATION LAUNCH

On February 1st, representatives from Fraunhofer IBMT, world-renowned German research institution, visited ROKIT, Inc to kick off the research partnership plans. On this day, the two groups discussed the development of novel bio-applications using INVIVO that build upon Fraunhofer IBMT’s existing technology on cell culturing and storage with ROKIT’s technology in 3D bioprinting. Some projects that will benefit from this synergy include retina regeneration and cardiomyocyte regeneration, for which project timelines were also discussed at this meeting. With the official launch of ROKIT EU in Germany and the kickoff meeting with Fraunhofer, there is much to look forward to in the upcoming year!

 

FRAUNHOFER IBMT, GERMANY VISITED ROKIT FOR CO-PROJECT ASSOCIATION

ROKIT, Inc. has entered into collaboration with Korea's leading surgeons (GNG Hospital and IDEA Clinic) with the aims of accelerating the clinical translation of 3D bioprinting technology in plastic and aesthetic reconstruction. According to the agreement, ROKIT will collaborate with the two institutions in the design and execution of pre-clinical and clinical studies as well as the development of novel personalized treatments using 3D printing. Projects in progress include skin regeneration for severe burn patients and cartilage regeneration for nose reconstruction and degenerative arthritis treatments. "Our bio-3D printers are being supplied to the world's leading research institutes, hospitals and biotechnology companies, and this year we look forward to translating this synergistic effort from the bench to the clinic for bringing into healthcare tailor-made artificial organ platforms for new lives and health," said ROKIT CEO Yoo Seok-Hwan. "We look forward to changing the face of healthcare together with experts in each field."

 

 

Our users share their stories. Below, we tried our best to put together a few of the representative case studies of INVIVO application. If you're interested in more, we welcome you to contact us at Skype ID: rokitinkorea for a Q&A chat!

 

If you believe INVIVO may help fulfill your research goals, whether they be in material science, cell / tissue biology, and other bioprinting explorations, please contact us. Thank you for your interest in ROKIT INVIVO. We imagine building your tomorrow together.

KeyTek Inc.

info@keytek-tr.com
 
PS. Below are media highlights of ROKIT INVIVO from the early phase of its development in 2016. But please note that we are continuing to innovate to become thefinest in our field.

1. Korea’s ROKIT Blasts Off into Bioprinting with New Bioprinter
2. ROKIT Releases a New 3D Bioprinter, Expected to “Change the Landscape” of Bioprinting
3. [Interview] ROKIT Seeks to Lead 3D Bio-Printer Market
 

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